Gallbladder cancer (GBC) is associated with various nongenetic and genetic factors. Lack of specific and sensitive diagnostic markers has significantly impacted the mortality of this disease. Here we discuss the recent discovery of epigenetic changes that show great promise as diagnostic biomarkers as well as potential therapeutic targets for GBC.

中文翻译：

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胆囊癌的表观遗传标志物。

胆囊癌（GBC）与各种非遗传和遗传因素有关。缺乏特异性和敏感的诊断标记已严重影响了该疾病的死亡率。在这里，我们讨论了表观遗传学变化的最新发现，这些发现显示出巨大的希望作为诊断性生物标志物以及GBC的潜在治疗靶标。