Sample preparation is a critical step in the separation of target analytes from complex matrices, which can influence the reliability and accuracy of the resulting analysis. Recent trends in sample preparation techniques are directed toward the automation and online coupling of sample preparation units, miniaturization, high efficiency, low costs, and reducing or eliminating solvent consumption. Microextraction techniques (METs) have all these advantages over conventional extraction methods. Thus, the application of METs in the analysis of different analytes from biological samples has increased significantly in recent years. Over time, many review articles have been written, which focus on the advantages, applications, and advances of these techniques for the analysis of various compounds in biological matrices. This paper presents a review of publications pertaining to the application of different types of METs in the analysis of biological samples along with their different aspects and a discussion of their future.

中文翻译：

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微萃取技术的生物分析应用：综述

样品制备是从复杂基质中分离目标分析物的关键步骤，会影响分析结果的可靠性和准确性。样品制备技术的最新趋势是朝着样品制备单元的自动化和在线耦合、小型化、高效率、低成本以及减少或消除溶剂消耗的方向发展。微萃取技术 (MET) 具有所有这些优于传统萃取方法的优势。因此，近年来 MET 在生物样品中不同分析物分析中的应用显着增加。随着时间的推移，撰写了许多评论文章，重点介绍这些技术在分析生物基质中的各种化合物方面的优势、应用和进展。