Reciprocated trust plays a critical role in forming and maintaining relationships, and has consistently been shown to implicate neural circuits involved in reward-related processing and social cognition. Less is known about neural network connectivity during social interactions involving trust, however, particularly as a function of closeness between an investor and a trustee. We examined network reactivity and connectivity in participants who played an economic trust game with close friends, strangers and a computer. Network reactivity analyses showed enhanced activation of the default-mode network (DMN) to social relative to non-social outcomes. A novel network psychophysiological interaction (nPPI) analysis revealed enhanced connectivity between the DMN and the superior frontal gyrus and superior parietal lobule when experiencing reciprocated vs violated trust from friends relative to strangers. Such connectivity tracked with differences in self-reported social closeness with these partners. Interestingly, reactivity of the executive control network (ECN), involved in decision processes, demonstrated no social vs non-social preference, and ECN-ventral striatum connectivity did not track social closeness. Taken together, these novel findings suggest that DMN interacts with components of attention and control networks to signal the relative importance of positive experiences with close others vs strangers.

中文翻译：

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社交互动过程中关系亲密程度对默认模式网络连接的影响。


相互信任在形成和维持关系方面发挥着至关重要的作用，并且一直被证明与参与奖励相关处理和社会认知的神经回路有关。然而，人们对涉及信任的社交互动期间的神经网络连接知之甚少，特别是作为投资者和受托人之间亲密程度的函数。我们检查了与亲密朋友、陌生人和计算机玩经济信任游戏的参与者的网络反应性和连接性。网络反应性分析表明，相对于非社交结果，默认模式网络（DMN）对社交的激活增强。一项新颖的网络心理生理学相互作用（nPPI）分析表明，当经历来自朋友相对于陌生人的相互信任和违背信任时，DMN 与额上回和顶上小叶之间的连接性增强。这种联系与这些合作伙伴自我报告的社交亲密程度的差异有关。有趣的是，参与决策过程的执行控制网络（ECN）的反应性没有表现出社交与非社交偏好，并且 ECN 腹侧纹状体连接不跟踪社交亲密程度。总而言之，这些新发现表明 DMN 与注意力和控制网络的组成部分相互作用，以表明与亲密他人和陌生人的积极经历的相对重要性。