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Applications of Functional Metal‐Organic Frameworks in Biosensors
Biotechnology Journal ( IF 3.2 ) Pub Date : 2020-04-09 , DOI: 10.1002/biot.201900424
Liping Du 1 , Wei Chen 1 , Ping Zhu 1 , Yulan Tian 1 , Yating Chen 1 , Chunsheng Wu 1
Affiliation  

In recent decades, fast advancements in the fields of metal‐organic frameworks (MOFs) are providing unprecedented opportunities for the development of novel functional MOFs for various biosensing applications. Exciting progress is achieved due to the combination of MOFs with various functional components, which introduces novel structures and new features to the MOFs‐based biosensing applications, such as higher stability, higher sensitivity, higher flexibility, and higher specificity. This review aims to be a comprehensive summary of the most recent advances in the development of functional MOFs for various biosensing applications, placing special attention on important contributions in recent 3 years. In this review, the most recent developments in design and synthesis of functional MOFs for biosensing applications are summarized. MOFs‐based biosensing applications are outlined according to the central roles of MOFs in biosensors, which include carriers of sensitive elements, enzyme‐mimic elements, electrochemical signaling, optical signaling, and gas sensing. Finally, the current challenges and future development trends of functional MOFs for biosensing applications are proposed and discussed.

中文翻译:

功能性金属有机骨架在生物传感器中的应用

近几十年来,金属有机框架(MOF)领域的快速发展为开发用于各种生物传感应用的新型功能性MOF提供了前所未有的机遇。MOF与各种功能组件的结合取得了令人兴奋的进展,这为基于MOF的生物传感应用带来了新颖的结构和新功能,例如更高的稳定性,更高的灵敏度,更高的灵活性和更高的特异性。这篇综述旨在对各种生物传感应用功能性MOF的最新发展进行全面总结,并特别关注近三年来的重要贡献。在这篇综述中,总结了用于生物传感应用的功能性MOF的设计和合成的最新进展。根据MOF在生物传感器中的核心作用,概述了基于MOF的生物传感应用,其中包括敏感元素,酶模拟元素,电化学信号,光学信号和气体传感的载体。最后,提出并讨论了用于生物传感应用的功能性MOF的当前挑战和未来的发展趋势。
更新日期:2020-04-09
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