The diagnosis of interstitial lung diseases (ILDs) can be straightforward for some experienced experts without biopsy data, but not so straightforward to others. In the context of suspected idiopathic pulmonary fibrosis (IPF), accurate non-invasive diagnosis requires recognition of the hallmark usual interstitial pneumonia (UIP) pattern on imaging, obviating lung biopsy [1, 2]. When the imaging pattern is “probable UIP”, the need for histopathology confirmation of a UIP pattern in surgical lung biopsy (SLB) is often debated, despite concordance between expert groups that SLB is not mandated for IPF diagnosis when the clinical setting is appropriate and multidisciplinary discussion has taken place [1–3]. The debate about the benefit of performing a surgical lung biopsy in patients with the probable UIP pattern needs every case to be viewed on an individual basis. This editorial attempts to bring some clarity to treating physicians and confused patients. http://bit.ly/2Qk517r

中文翻译：

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特发性肺纤维化中典型和可能的常见间质性肺炎模式对预后的影响：关于活检的争论是星球大战传奇吗？

对于一些没有活检数据的经验丰富的专家来说，间质性肺病 (ILD) 的诊断可能很简单，但对其他人来说就不是那么简单了。在疑似特发性肺纤维化 (IPF) 的情况下，准确的非侵入性诊断需要在影像学上识别标志性的常见间质性肺炎 (UIP) 模式，从而避免肺活检 [1, 2]。当成像模式是“可能的 UIP”时，尽管专家组一致认为当临床环境合适且 SLB 不强制用于 IPF 诊断，但在外科肺活检 (SLB) 中是否需要组织病理学确认 UIP 模式仍存在争议。进行了多学科讨论 [1-3]。关于对可能的 UIP 模式的患者进行外科肺活检的好处的争论需要根据个体情况来看待每个病例。这篇社论试图为治疗医生和困惑的患者带来一些清晰度。http://bit.ly/2Qk517r