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Adrenal Incidentaloma.
Endocrine Reviews ( IF 22.0 ) Pub Date : 2020-04-08 , DOI: 10.1210/endrev/bnaa008
Mark Sherlock 1, 2 , Andrew Scarsbrook 3 , Afroze Abbas 4 , Sheila Fraser 5 , Padiporn Limumpornpetch 6 , Rosemary Dineen 1, 2 , Paul M Stewart 6
Affiliation  

An adrenal incidentaloma is now established as a common endocrine diagnosis that requires a multidisciplinary approach for effective management. The majority of patients can be reassured and discharged, but a personalized approach based upon image analysis, endocrine workup, and clinical symptoms and signs are required in every case. Adrenocortical carcinoma remains a real concern but is restricted to <2% of all cases. Functional adrenal incidentaloma lesions are commoner (but still probably <10% of total) and the greatest challenge remains the diagnosis and optimum management of autonomous cortisol secretion. Modern-day surgery has improved outcomes and novel radiological and urinary biomarkers will improve early detection and patient stratification in future years to come.

中文翻译:

 肾上腺偶发瘤。


肾上腺偶发瘤现已成为一种常见的内分泌诊断,需要采用多学科方法进行有效治疗。大多数患者可以放心出院,但每种情况都需要基于图像分析、内分泌检查以及临床症状和体征的个性化方法。肾上腺皮质癌仍然是一个真正令人担忧的问题,但仅限于所有病例的 <2%。功能性肾上腺偶发瘤病变较为常见(但仍可能占总数的 <10%),最大的挑战仍然是自主皮质醇分泌的诊断和最佳管理。现代手术已经改善了结果,新型放射学和泌尿生物标志物将在未来几年改善早期检测和患者分层。
更新日期:2020-04-08
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