Hyaluronic acid (HA)-curcumin electrospun fibers exhibiting antimicrobial, anti-inflammatory, and anti-tumorigenic activity were fabricated. It is shown that a metachromatic complex between HA and curcumin is formed in a water-organic medium, thus stabilizing the electro-spinning process and improving the fiber characteristics. The polymer fibers prepared at a voltage of 26 kV have an average diameter of 0.296 μm (at a fiber diameter distribution from 0.146 to 0.630 μm). These HA-curcumin fibers can be widely used both in regenerative medicine and in the development of drug delivery systems.

中文翻译：

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透明质酸——姜黄素电纺纤维

制备了具有抗菌、抗炎和抗肿瘤发生活性的透明质酸 (HA)-姜黄素电纺纤维。结果表明，HA和姜黄素之间的异染复合物在水-有机介质中形成，从而稳定静电纺丝过程并改善纤维特性。在26kV电压下制备的聚合物纤维的平均直径为0.296μm（纤维直径分布为0.146-0.630μm）。这些 HA-姜黄素纤维可广泛用于再生医学和药物递送系统的开发。