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Encapsulation of diagnostic dyes in the polysaccharide matrix modified by carbon nanotubes
Russian Chemical Bulletin ( IF 1.7 ) Pub Date : 2020-03-01 , DOI: 10.1007/s11172-020-2803-x
L. R. Bogdanova , A. O. Makarova , O. S. Zueva , L. Ya. Zakharova , Yu. F. Zuev

The effect of carbon nanotubes (CNTs) on the morphology and properties of alginate hydrogel was studied. The addition of CNTs leads to a change in the structural characteristics of the hydrogel, which is expressed in a decrease in the pore size and gaining a more uniformity by the internal structure. To study the encapsulating properties of the designed compositions, a set of dyes was used that are traditionally applied for testing the drug release rate. It was found that the CNTs do not affect the efficiency of inclusion and the release rate of the anionic and neutral dyes. The change in the kinetics of cationic dye release is caused by the reinforcing effect of the CNTs on the alginate hydrogel and a change in its morphological characteristics.

中文翻译:

碳纳米管修饰的多糖基质中诊断染料的封装

研究了碳纳米管(CNTs)对海藻酸盐水凝胶形态和性能的影响。碳纳米管的加入导致水凝胶结构特性的变化,表现为孔径减小,内部结构更加均匀。为了研究设计的组合物的包封特性,使用了一组传统上用于测试药物释放速率的染料。发现碳纳米管不影响包含效率和阴离子和中性染料的释放速率。阳离子染料释放动力学的变化是由碳纳米管对藻酸盐水凝胶的增强作用及其形态特征的变化引起的。
更新日期:2020-03-01
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