Horizontal gene transfer (HGT) facilitates spead of antibiotic resistance elements. In this issue of Cell Host & Microbe, Domenech et al. discover that compounds disrupting proton motive force block natural competence (COM) and interrupt intraspecies HGT and exchange of antibiotic resistance. Such strategies might minimize clinical spread of antibiotic resistance.

中文翻译：

---

笼养和COM对抗抗生素耐药性。

水平基因转移（HGT）促进了抗生素抗性元件的发展。在本期《细胞宿主与微生物》中，Domenech等人。发现破坏质子动力的化合物会阻断自然能力（COM）并干扰种内HGT和抗生素抗性交换。这样的策略可以使抗生素耐药性的临床传播最小化。