In this paper, a novel mercury-free electrochemical probe was constructed for the trace determination of octamethylcyclotetrasiloxane (D4) in some biological fluids by adsorptive stripping voltammetry. The platform is based on the adsorptive accumulation of Ni(II) onto a carbon paste electrode modified with citrate stabilized Fe3O4 (Cit-Fe3O4) and dimethylglyoxime (DMG). It was shown that trace levels of D4 enhance the electrochemical adsorptive stripping signal of Ni(II) on the electrode platform. It was shown that electrochemical signals are proportional to concentrations of D4. The supporting electrolyte, pH and instrumental parameters associated with the electrode response, including scan rate, accumulation potential and deposition time were optimized. The electrode platform demonstrated well resolved, reproducible peaks, with relative standard deviation (RSD) of 3.8% and detection limit (3Sb/m) of 27.0 ng/mL. The sensor exhibited good D4 detection and quantification in human blood plasma and urine samples.

中文翻译：

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柠檬酸盐稳定的 Fe3O4/DMG 改性碳糊电极用于测定水泥厂工人血浆和尿液样品中的八甲基环四硅氧烷。

本文构建了一种新型无汞电化学探针，用于吸附溶出伏安法对一些生物体液中的八甲基环四硅氧烷（D4）进行痕量测定。该平台基于 Ni(II) 在用柠檬酸盐稳定的 Fe3O4 (Cit-Fe3O4) 和二甲基乙二肟 (DMG) 改性的碳糊电极上的吸附积累。结果表明，微量 D4 增强了电极平台上 Ni(II) 的电化学吸附剥离信号。结果表明，电化学信号与 D4 的浓度成正比。优化了与电极响应相关的支持电解质、pH 和仪器参数，包括扫描速率、累积电位和沉积时间。电极平台表现出良好的分辨、可重现的峰，相对标准偏差 (RSD) 为 3.8%，检测限 (3Sb/m) 为 27.0 ng/mL。该传感器在人体血浆和尿液样本中表现出良好的 D4 检测和量化。