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Outcome in dogs undergoing adrenalectomy for small adrenal gland tumours without vascular invasion
Veterinary and Comparative Oncology ( IF 2.3 ) Pub Date : 2020-03-05 , DOI: 10.1111/vco.12587
Jacqueline V J Cavalcanti 1, 2 , Owen T Skinner 3 , Philipp D Mayhew 4 , James C Colee 5 , Sarah E Boston 6
Affiliation  

Veterinary studies have reported the outcome of adrenalectomies in dogs; however, these studies typically include a wide variety of adrenal tumour sizes, including cases with or without vascular invasion. The purpose of this study was to report outcome in a cohort of dogs with histologically confirmed small adrenal tumours without vascular invasion treated with adrenalectomy. This retrospective study was conducted using data from the University of Florida and University of California‐Davis databases between 2010 and 2017. Dogs were included if they underwent excision of an adrenal gland tumour with a maximal diameter ≤ 3 cm, without evidence of vascular invasion to any location as assessed via computed tomography. Fifty‐one dogs met the inclusion criteria. The short‐term survival rate of dogs undergoing adrenalectomy was 92.2%, and one‐year disease‐specific survival was 83.3%. Twenty‐eight of 51 (54.9%) dogs were diagnosed with a malignancy. Minor complications were observed commonly intra‐operatively and post‐operatively. Major complications were observed in six dogs, and included sudden death, respiratory arrest, acute kidney injury, haemorrhage, hypotension and aspiration pneumonia. Short‐term mortality occurred in four dogs. Sudden death and haemorrhage were the most common major complications leading to death. While adrenalectomy is sometimes controversial because of the high perioperative mortality rates previously reported, the results of this study support that adrenalectomy for small tumours with no vascular invasion can be performed with low risk.

中文翻译:

犬接受肾上腺切除术治疗无血管侵犯的小肾上腺肿瘤的结果

兽医研究报告了狗肾上腺切除术的结果;然而,这些研究通常包括各种大小的肾上腺肿瘤,包括有或没有血管侵犯的病例。本研究的目的是报告一组经肾上腺切除术治疗且组织学证实无血管侵犯的小肾上腺肿瘤的狗的结果。这项回顾性研究是使用佛罗里达大学和加州大学戴维斯分校 2010 年至 2017 年数据库中的数据进行的。通过计算机断层扫描评估的任何位置。51 只狗符合纳入标准。接受肾上腺切除术的犬的短期存活率为 92.2%,一年疾病特异性生存率为 83.3%。51 只狗中有 28 只 (54.9%) 被诊断出患有恶性肿瘤。术中和术后常见的轻微并发症。在六只狗中观察到主要并发症,包括猝死、呼吸停止、急性肾损伤、出血、低血压和吸入性肺炎。四只狗发生了短期死亡。猝死和出血是导致死亡的最常见的主要并发症。虽然由于先前报道的围手术期死亡率高,肾上腺切除术有时会引起争议,但本研究的结果支持无血管侵犯的小肿瘤的肾上腺切除术可以以低风险进行。术中和术后常见的轻微并发症。在六只狗中观察到主要并发症,包括猝死、呼吸停止、急性肾损伤、出血、低血压和吸入性肺炎。四只狗发生了短期死亡。猝死和出血是导致死亡的最常见的主要并发症。虽然由于先前报道的围手术期死亡率高,肾上腺切除术有时会引起争议,但本研究的结果支持无血管侵犯的小肿瘤的肾上腺切除术可以以低风险进行。术中和术后常见的轻微并发症。在六只狗中观察到主要并发症,包括猝死、呼吸停止、急性肾损伤、出血、低血压和吸入性肺炎。四只狗发生了短期死亡。猝死和出血是导致死亡的最常见的主要并发症。虽然由于先前报道的围手术期死亡率高,肾上腺切除术有时会引起争议,但本研究的结果支持无血管侵犯的小肿瘤的肾上腺切除术可以以低风险进行。四只狗发生了短期死亡。猝死和出血是导致死亡的最常见的主要并发症。虽然由于先前报道的围手术期死亡率高,肾上腺切除术有时会引起争议,但本研究的结果支持无血管侵犯的小肿瘤的肾上腺切除术可以以低风险进行。四只狗发生了短期死亡。猝死和出血是导致死亡的最常见的主要并发症。虽然由于先前报道的围手术期死亡率高,肾上腺切除术有时会引起争议,但本研究的结果支持无血管侵犯的小肿瘤的肾上腺切除术可以以低风险进行。
更新日期:2020-03-05
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