Epigenetic mechanisms influence the development and maintenance of complex phenotypes and may also contribute to the evolution of species–specific phenotypes. With respect to skeletal traits, little is known about the gene regulation underlying these hard tissues or how tissue‐specific patterns are associated with bone morphology or vary among species. To begin exploring these topics, this study evaluates one epigenetic mechanism, DNA methylation, in skeletal tissues from five nonhuman primate species which display anatomical and locomotor differences representative of their phylogenetic groups.

中文翻译：

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灵长类动物骨骼DNA甲基化和股骨形态的种内和种间研究。

表观遗传机制影响复杂表型的发展和维持，也可能有助于特定物种表型的演变。关于骨骼特征，对于这些硬组织的基因调控或组织特异性模式与骨形态或物种之间的差异知之甚少。为了开始探索这些主题，本研究评估了来自五个非人类灵长类物种的骨骼组织中的一种表观遗传机制，即DNA甲基化，这些物种显示出代表其系统发生群体的解剖学和运动差异。