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Intravital imaging of host-parasite interactions in organs of the thoracic and abdominopelvic cavities.
Cellular Microbiology ( IF 2.6 ) Pub Date : 2020-04-05 , DOI: 10.1111/cmi.13201
Mariana De Niz 1, 2 , Tânia Carvalho 2 , Carlos Penha-Gonçalves 3 , Carolina Agop-Nersesian 1
Affiliation  

Infections with protozoan and helminthic parasites affect multiple organs in the mammalian host. Imaging pathogens in their natural environment takes a more holistic view on biomedical aspects of parasitic infections. Here, we focus on selected organs of the thoracic and abdominopelvic cavities most commonly affected by parasites. Parasitic infections of these organs are often associated with severe medical complications or have health implications beyond the infected individual. Intravital imaging has provided a more dynamic picture of the host-parasite interplay and contributed not only to our understanding of the various disease pathologies, but has also provided fundamental insight into the biology of the parasites.

中文翻译:

胸腔和腹腔腔器官内宿主-寄生虫相互作用的活体成像。

原生动物和蠕虫寄生虫感染会影响哺乳动物宿主中的多个器官。在自然环境中对病原体进行成像可以对寄生虫感染的生物医学方面有更全面的了解。在这里,我们集中于最常受寄生虫感染的胸腔和腹腔腔的选定器官。这些器官的寄生虫感染通常与严重的医疗并发症相关,或对受感染者具有健康影响。活体成像为宿主-寄生虫的相互作用提供了更加动态的图像,不仅有助于我们对各种疾病病理学的理解,而且还提供了对寄生虫生物学的基本了解。
更新日期:2020-04-05
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