Bone regeneration is a complex process modulated by multiple growth factors and hormones during long regeneration period; thus, designing biomaterials with the capacity to deliver multiple bioactive molecules and obtain sustained release has gained an increasing popularity in recent years. This study is aimed to evaluate the effect of a novel core‐shell electrospun fibre loaded with dexamethasone (DEX) and bone morphogenetic protein‐2 (BMP‐2) on bone regeneration.

中文翻译：

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负载生物活性分子的电纺核壳纤维对临界尺寸颅骨骨缺损重建的协同作用——协同释放对骨形成的影响


骨再生是一个复杂的过程，在漫长的再生过程中受到多种生长因子和激素的调节；因此，设计能够传递多种生物活性分子并获得持续释放的生物材料近年来越来越受欢迎。本研究旨在评估负载地塞米松（DEX）和骨形态发生蛋白-2（BMP-2）的新型核壳电纺纤维对骨再生的影响。