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Non‐enzymatic reaction of carnosine and glyceraldehyde‐3‐phosphate accompanies metabolic changes of the pentose phosphate pathway
Cell Proliferation ( IF 5.9 ) Pub Date : 2019-10-19 , DOI: 10.1111/cpr.12702
Henry Oppermann 1 , Claudia Birkemeyer 2 , Jürgen Meixensberger 1 , Frank Gaunitz 1
Affiliation  

Carnosine (β‐alanyl‐l‐histidine) is a naturally occurring dipeptide that selectively inhibits cancer cell growth, possibly by influencing glucose metabolism. As its precise mode of action and its primary targets are unknown, we analysed carnosine's effect on metabolites and pathways in glioblastoma cells.

中文翻译:

肌肽和甘油醛-3-磷酸的非酶促反应伴随磷酸戊糖途径的代谢变化

肌肽(β-丙氨酰-l-组氨酸)是一种天然存在的二肽,可能通过影响葡萄糖代谢来选择性抑制癌细胞生长。由于其精确的作用方式及其主要靶标未知,我们分析了肌肽对胶质母细胞瘤细胞代谢物和途径的影响。
更新日期:2019-10-19
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