The sequence of initial tissue ischaemia and consecutive blood flow restoration leads to ischaemia/reperfusion (I/R) injury, which is typically characterized by a specific inflammatory response. Migrating monocytes seem to mediate the immune response in ischaemic tissues and influence detrimental as well as regenerative effects during I/R injury.

中文翻译：

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体外缺血/再灌注的人单核细胞抑制血管生成和伤口愈合

初始组织缺血和连续血流恢复的顺序导致缺血/再灌注 (I/R) 损伤，其通常以特定的炎症反应为特征。迁移的单核细胞似乎介导缺血组织中的免疫反应，并影响 I/R 损伤期间的有害和再生作用。