The aim of this work was to microencapsulate vitamin B1 by spray‐drying using different encapsulating agents (arabic gum, carrageenan, chitosan, maltodextrin, modified chitosan, modified starch, pectin, sodium alginate, and xanthan) and to characterize the microcapsules and study their release. Microcapsules with a 0.25% (w/w) content of vitamin B1 were produced. The product yield results ranged from 17%‐52% and the encapsulation efficiency from 66%‐100%. Three categories of morphology, regular spherical shape, irregular spherical shape with rough surface, and irregular shape, were identified. Their sizes, determined by laser granulometry, ranged from 0.11‐1.32 μm, in terms of number distribution, and from 3.76‐34.43 μm, in volume distribution. Controlled release studies were performed by spectrophotometric analysis, in deionized water (20°C) and simulated gastric fluid (37°C). Different release behaviours were observed from just 10 seconds (modified starch) up to more than 24 hours (xanthan). Kinetic models such as zero‐order, first‐order, Higuchi, Korsmeyer‐Peppas, and Weibull were applied. The Weibull model showed the best fitting with the experimental data. All release tests were repeated after 4 months and showed good stability over time. A mass loss of vitamin B1 lower than 20% was detected. This study demonstrates the possibility of encapsulating vitamin B1 using different encapsulating agents by a spray‐drying technique. Depending on the intended applications, for fast release, adequate results were obtained for maltodextrin, arabic gum, modified chitosan, and sodium alginate, and for slow release, adequate results were only obtained for chitosan and pectin.

中文翻译：

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使用不同的生物聚合物作为墙体材料，通过喷雾干燥工艺生产维生素B1微粒

这项工作的目的是通过使用不同的包封剂（阿拉伯胶，角叉菜胶，壳聚糖，麦芽糊精，改性壳聚糖，改性淀粉，果胶，藻酸钠和黄原胶）喷雾干燥来微囊化维生素B1，并对微胶囊进行表征并对其进行研究释放。制备了具有0.25％（w / w）含量的维生素B1的微胶囊。产品成品率范围为17％-52％，封装效率为66％-100％。确定了三类形态：规则球形，具有粗糙表面的不规则球形和不规则形状。通过激光粒度测定法确定其尺寸，其数量分布范围为0.11-1.32μm，体积分布范围为3.76-34.43μm。通过分光光度分析进行控释研究，在去离子水（20°C）和模拟胃液（37°C）中。从仅仅10秒（改性淀粉）到超过24小时（黄原胶），都观察到了不同的释放行为。动力学模型，如零阶，一阶，Higuchi，Korsmeyer-Peppas和Weibull。威布尔模型显示出与实验数据的最佳拟合。4个月后重复所有释放测试，并显示出良好的稳定性。检测到维生素B1的质量损失低于20％。这项研究证明了通过喷雾干燥技术使用不同的封装剂来封装维生素B1的可能性。根据预期的应用，对于快速释放，麦芽糖糊精，阿拉伯胶，改性壳聚糖和海藻酸钠以及缓慢释放均获得了足够的效果，