Multi-objective optimisation of the bio-inspired lightweight structure is developed by response surface methodology (RSM) and non-dominated sorting genetic algorithm II (NSGA-II) for future applications in the aerospace and military fields. Multilayer bio-inspired sandwich structures of Ti6Al4V alloy are designed and fabricated by selective laser melting (SLM). Results show that the bio-inspired sandwich structures can be optimized by RSM and NSGA-II with a relative error rate of experiment and response value less than 10%. The bio-inspired sandwich structures with different core-arranged configurations were destroyed layer by layer under out-of-plane loadings with a primary failure mode of the core breaking. Increasing the layer number of cores can improve the comprehensive mechanical performances of multilayer bio-inspired sandwich structures with cross-arranged configurations but will decrease the energy absorption capacity of those with parallel-arranged configurations. Furthermore, the two-layered bio-inspired sandwich structure under cross-arranged configurations has the most excellent comprehensive performances with the specific energy absorption of 9.16 × 10³ J/kg and the energy absorption of 154.80 J, respectively.

通过响应面方法（RSM）和非支配排序遗传算法II（NSGA-II）开发了受生物启发的轻型结构的多目标优化，以供将来在航空航天和军事领域中应用。Ti6Al4V合金的多层生物启发三明治结构是通过选择性激光熔化（SLM）设计和制造的。结果表明，可通过RSM和NSGA-II优化生物启发的三明治结构实验的相对错误率和响应值小于10％。具有不同芯排列结构的生物启发式三明治结构在平面外载荷下以芯断裂的主要破坏模式逐层破坏。增加芯的层数可以改善具有交叉排列构型的多层生物启发三明治结构的综合机械性能，但会降低具有平行排列构型的多层夹心结构的能量吸收能力。此外，交叉排列结构的两层生物启发三明治结构具有最优异的综合性能，单位能量吸收分别为9.16×10 ³  J / kg和154.80J。