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One-pot, solvent-free facile stereoselective synthesis of rhodanine–furan hybrids from renewable resources
Journal of Sulfur Chemistry ( IF 2.2 ) Pub Date : 2019-12-15 , DOI: 10.1080/17415993.2019.1702196
Leila Sabahi-Agabager 1 , Farough Nasiri 1
Affiliation  

ABSTRACT In this study, a one-pot, solvent-free stereoselective reaction was started between primary amines, carbon disulfide, ethyl bromoacetate, and furan derivatives derived from sugars at room temperature, which was completed within 10 min to produce rhodanine–furan hybrid molecules in good to high yields. The presence of the chloromethyl group in products derived from chloromethylfurfural (CMF) made it possible for the substitution of other functional groups such as amine group. GRAPHICAL ABSTRACT

中文翻译:

从可再生资源中一锅法、无溶剂简便立体选择性合成罗丹宁-呋喃杂化物

摘要 在本研究中,伯胺、二硫化碳、溴乙酸乙酯和由糖衍生的呋喃衍生物在室温下开始一锅、无溶剂立体选择性反应,该反应在 10 分钟内完成以产生罗丹宁-呋喃杂化分子高产。氯甲基糠醛 (CMF) 衍生产品中氯甲基的存在使得其他官能团如胺基的取代成为可能。图形概要
更新日期:2019-12-15
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