ABSTRACT The essential oils of the aerial parts and roots (APEO and REO) of Pulicaria vulgaris subsp. dentata (Sm.) Batt. were analyzed by GC and GC-MS. Twenty-one compounds (97.2% of the total oil composition) were identified in the REO, with γ-irone (39.2%), 7-epi-silphiperfol-5-ene (19.3%), 2,5-dimethoxy-p-cymene (8.5%) and γ-himachalene (8.0%) as main constituents. The APEO was rich in cis-β-guaiene (59.7%), together with eighteen other compounds, accounting for 93.2% of the total oil composition. Antiradical and enzymatic antioxidant properties of the isolated oils were also evaluated. The REO exhibited the highest antioxidant activity using DPPH, ABTS, catalase and paraoxonase tests. Antimicrobial, cytotoxic and tyrosinase inhibiting properties of these essential oils have been also studied. APEO exhibited significant activity towards Pseudomonas syringae and Agrobacterium tumefaciens. The REO showed the most significant cytotoxic effect against HeLa cell line and the highest tyrosinase inhibition activity.

中文翻译：

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Pulicaria vulgaris subsp. 精油的化学成分和生物活性。dentata (Sm.) Batt. 在突尼斯成长

摘要 Pulicaria vulgaris subsp 地上部分和根（APEO 和 REO）的精油。dentata (Sm.) Batt. GC 和 GC-MS 分析。在 REO 中鉴定出 21 种化合物（占总油成分的 97.2%），包括 γ-铁酮（39.2%）、7-epi-silphiperfol-5-ene（19.3%）、2,5-二甲氧基-p-伞花烃 (8.5%) 和 γ-喜马香烯 (8.0%) 作为主要成分。APEO富含顺式β-愈创木烯（59.7%），以及其他18种化合物，占总油成分的93.2%。还评估了分离油的抗自由基和酶促抗氧化特性。使用 DPPH、ABTS、过氧化氢酶和对氧磷酶测试，REO 表现出最高的抗氧化活性。还研究了这些精油的抗菌、细胞毒性和酪氨酸酶抑制特性。APEO 对丁香假单胞菌和根癌农杆菌具有显着的活性。REO 对 HeLa 细胞系显示出最显着的细胞毒作用和最高的酪氨酸酶抑制活性。