The first attempt at modelling of deformation density was in 1950 when R. Franklin published her observation of the influence of the bonding effects on the intensities of structure factors and suggested to describe the deformation density by point scatterers at the C–C bonds.

中文翻译：

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介绍大分子原子模型的晶体学细化。附录

变形密度建模的第一次尝试是在 1950 年，当时 R. Franklin 发表了她对键合效应对结构因子强度影响的观察，并建议通过 C-C 键处的点散射体来描述变形密度。