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Urban-Rural Differences in Bone Mineral Density and its Association with Reproductive and Menstrual Factors Among Older Women.
Calcified Tissue International ( IF 4.2 ) Pub Date : 2020-03-16 , DOI: 10.1007/s00223-020-00681-8
Jing Wang 1, 2 , Weiqiang Zhang 1, 2 , Xiaoyun Wang 1 , Chenguang Li 1, 2 , Jinlong Li 1, 2 , Yongjian Zhao 1, 2 , Lin Chen 1, 2 , Xiaofeng Qi 1, 2 , Liang Qiao 1, 2 , Weiwei Da 1, 2 , Li Liu 1, 2 , Chongqing Xu 1, 2 , Sen Zhu 1, 2 , Yimian Li 1, 2 , Hao Zhang 1, 2 , Nannan Sha 1, 2 , Qiang Wang 1, 2 , Yin Zhu 1, 2 , Jianxing Luo 1, 2 , Xuejun Cui 1, 2 , Qianqian Liang 1, 2 , Sheng Lu 1, 2 , Qi Shi 1, 2, 3 , Yongjun Wang 1, 2, 3 , Bing Shu 1, 2
Affiliation  

PURPOSE This study aimed to compare the bone mineral density (BMD) of older women living in rural and urban areas, and evaluate the potential factors affecting the risk of osteoporosis. METHODS We recruited 574 women aged 65 years or older from rural areas and 496 from urban areas in Shanghai, China. The BMD values of the lumbar vertebrae and total left hip were measured by a dual energy X-ray absorptiometry densitometer. We also recorded information about education level, family income, medications, reproductive and menstrual history, diet, smoking, and alcohol consumption. RESULTS Women in urban areas had significantly higher BMD in their lumbar spine, and there was a dramatic increase in the proportion of women with osteoporosis in rural areas. The age at menarche was significantly higher among women living in rural areas, and there were more years from menarche to menopause among urban women. Rural women had significantly higher numbers of both pregnancies and parity, and a significantly lower age at first parity. In multiple linear regression analyses, years from menarche to menopause was independently related to high lumbar spine BMD, while age at menarche and parity was independently related to low lumbar spine BMD. CONCLUSION More older women in rural areas had osteoporosis. Later menarche, less years from menarche to menopause and higher parity might partially contribute to decreased BMD among women in rural areas. More attention should be paid to women in rural areas to prevent bone loss and further bone and health impairment.
更新日期:2020-03-16
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