Surgical resection represents the primary treatment option for patients suffering from intracranial meningioma. However, early postoperative complications significantly worsen initial favorable postoperative outcomes. Therefore, the ability to preoperatively assess potential risk factors for early postoperative unfavorable events is important to preselect critical patients who might require special attention during clinical management. In the current study, we therefore analyzed our institutional database in order to identify risk factors associated with early postoperative complications after initial meningioma resection. Between 2014 and 2017, 202 patients with intracranial supratentorial meningioma were surgically treated at the authors’ institution. Early postoperative complications were defined as any postoperative event requiring further surgical measures within 30 days following initial meningioma resection. A multivariate analysis was performed to identify independent risk factors associated with postoperative complications after surgical meningioma therapy. Overall, 13 out of 202 meningioma patients developed early postoperative complications (6%). The multivariate analysis revealed obesity in terms of elevated body mass index (BMI ≥ 30 kg/m²) (p = 0.03), the presence of atrial fibrillation (p = 0.001) as well as the preoperative Karnofsky Performance Status Scale < 70% (p = 0.004) as independent predictors for early postoperative complications in the course of supratentorial meningioma resection. Obesity is associated with a higher risk of postoperative unfavorable events that require further surgical treatment. Furthermore, the present study identifies several additional risk factors for the development of early postoperative complications after intracranial meningioma resection enabling to preoperatively select for high-risk patients that might require special attention in clinical and surgical management.

手术切除是颅内脑膜瘤患者的主要治疗选择。但是，术后早期并发症明显恶化了初始良好的术后效果。因此，术前评估术后早期不良事件的潜在危险因素的能力对于预选在临床治疗期间可能需要特别注意的危重患者非常重要。因此，在当前的研究中，我们分析了机构数据库，以确定与初次脑膜瘤切除术后早期并发症相关的危险因素。在2014年至2017年之间，作者所在机构对202例颅内幕上脑膜瘤患者进行了手术治疗。术后早期并发症的定义是指任何需要在初次脑膜瘤切除后30天内采取进一步手术措施的术后事件。进行多变量分析以鉴定与外科脑膜瘤治疗后术后并发症相关的独立危险因素。总体而言，在202名脑膜瘤患者中，有13名发生了早期术后并发症（6％）。多元分析显示，肥胖症的体重指数较高（BMI≥30 kg / m²）（p  = 0.03），房颤的存在（p  = 0.001）以及术前Karnofsky行为状态量表<70％（p  = 0.004）作为幕上膜脑膜瘤切除术早期术后并发症的独立预测因子。肥胖与需要进一步手术治疗的术后不良事件发生的风险较高相关。此外，本研究确定了颅内脑膜瘤切除术后早期术后并发症发展的其他一些危险因素，从而能够在术前选择可能在临床和外科治疗中需要特别注意的高危患者。