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Is the unruptured intracranial aneurysm treatment score (UIATS) sensitive enough to detect aneurysms at risk of rupture?
Neurosurgical Review ( IF 2.5 ) Pub Date : 2020-03-12 , DOI: 10.1007/s10143-020-01246-x
Silvia Hernández-Durán 1 , Dorothee Mielke 1 , Veit Rohde 1 , Vesna Malinova 1
Affiliation  

To evaluate if the unruptured intracranial aneurysm treatment score (UIATS) is a sensitive tool to detect aneurysms at risk of rupture, we conducted an a posteriori retrospective study on ruptured intracranial aneurysms. We performed a retrospective analysis of adult patients admitted to our center from January 2010 to April 2016 with aneurysmal subarachnoid hemorrhage. The UIATS was applied to all ruptured aneurysms. Patients for whom the UIATS recommended treatment were labeled as “true positives,” whereas patients for whom the UIATS recommended observation were labeled as “false negatives.” Patients for whom the UIATS was inconclusive were excluded from the final analysis. Based on the UIATS recommendation, a sensitivity analysis was performed. A total of 262 patients with aneurysmal subarachnoid hemorrhage were screened. Of these, 212 were included in our analysis. Median age was 53 years (23–90). Most patients were females (n = 134, 63%), with an equal distribution between low-grade and high-grade hemorrhages (Hunt & Hess ≥ 3 n = 107, 50%). UIATS recommended treatment in n = 52, 25% cases (TP), was inconclusive in n = 93, 44% (excluded), and recommended observation in n = 67, 32% (FN). Based on these data, the UIATS showed a sensitivity of 44% (CI 35–53%). The UIATS exhibits rather low sensitivity for detecting aneurysms at risk of rupture.



中文翻译:

未破裂颅内动脉瘤治疗评分 (UIATS) 是否足够敏感以检测有破裂风险的动脉瘤?

为了评估未破裂颅内动脉瘤治疗评分 (UIATS) 是否是检测有破裂风险的动脉瘤的敏感工具,我们对破裂的颅内动脉瘤进行了一项后验回顾性研究。我们对 2010 年 1 月至 2016 年 4 月因动脉瘤性蛛网膜下腔出血入院的成年患者进行了回顾性分析。UIATS 适用于所有破裂的动脉瘤。UIATS 推荐治疗的患者被标记为“真阳性”,而 UIATS 推荐观察的患者被标记为“假阴性”。UIATS 不确定的患者被排除在最终分析之外。根据 UIATS 的建议,进行了敏感性分析。共筛查了 262 名动脉瘤性蛛网膜下腔出血患者。这些,212 个被纳入我们的分析。中位年龄为 53 岁 (23-90)。大多数患者为女性(n  = 134, 63%),低级别和高级别出血之间的分布相等(Hunt & Hess ≥ 3 n  = 107, 50%)。UIATS在推荐的治疗Ñ  = 52,25%的病例(TP),在不确定的Ñ  = 93,44%(不含),和在推荐的观测Ñ  = 67,32%(FN)。基于这些数据,UIATS 的敏感性为 44% (CI 35–53%)。UIATS 在检测有破裂风险的动脉瘤方面表现出相当低的灵敏度。

更新日期:2020-03-12
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