Exposure to mercury is one of the major global health concerns due to its stability, bioaccumulation and high toxicity. Therefore, the present study was conducted to assess the mean mercury level in hair and breast milk (BM) of Iranian lactating mothers (ILMs) through meta-analysis technique. We conducted a systematic literature search in online electronic databases included main domestic databases (SID, Magiran, Iran medex, Medlib and ISC) and international databases (Embase, Scopus and PubMed) for studies published between 2000 up 2018. Each process of research and evaluation of articles based on inclusion and exclusion criteria is done by two researchers, individually. From10 studies entered to meta-analysis process including 556 ILM, the mean hair mercury level (HML) and mean milk mercury level (MML) was estimated to be 0.15 μg/g (95 CI: 0.11–0.19, I2: 47.6%, P: 0.028) and 0.51 μg/l (95 CI: 0.28–0.74, I2: 1.9%, P: 0.421), respectively. In this meta-analysis, the mean HML and mean MML were estimated to be lower than the standard of World Health Organization (WHO). Although the mean mercury level in hair and BM of ILMs was lower than the WHO standard, but due to toxicity and serious concern of health, management and Periodic monitor are recommended in different cities of the country for evaluate the mercury levels in hair and BM of ILMs and to estimate the infant’s exposure.

中文翻译：

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伊朗哺乳期母亲的头发和母乳中的汞含量：系统评价和荟萃分析。

由于汞的稳定性，生物蓄积性和高毒性，汞暴露是全球主要的健康问题之一。因此，本研究旨在通过荟萃分析技术评估伊朗哺乳母亲（ILM）的头发和母乳（BM）中的平均汞含量。我们对在线电子数据库进行了系统的文献搜索，包括主要的国内数据库（SID，Magiran，伊朗medex，Medlib和ISC）和国际数据库（Embase，Scopus和PubMed），以进行2000年至2018年之间发表的研究。研究和评估的每个过程基于包含和排除标准的文章的撰写由两名研究人员分别完成。进入荟萃分析过程的10项研究（包括556 ILM），平均头发汞含量（HML）和平均牛奶汞含量（MML）估计为0.15μg/ g（95 CI：0）。11–0.19，I2：47.6％，P：0.028）和0.51μg/ l（95 CI：0.28–0.74，I2：1.9％，P：0.421）。在这项荟萃分析中，估计的平均HML和平均MML低于世界卫生组织（WHO）的标准。虽然ILM的头发和BM中的平均汞含量低于WHO标准，但由于毒性和对健康的严重关注，建议在该国不同城市进行管理和定期监测以评估头发和BM中的汞含量ILM和估计婴儿的暴露程度。