In this report, HLA polymorphisms (A, B, DRB1 and DQB1 loci) were determined in 149 unrelated Iraqi Arab potential bone marrow and kidney donors. Molecular genotyping was carried out by polymerase chain reaction followed by specific oligonucleotide probe hybridizations. Data were analyzed by Arlequin software. HLA-A, -B and -DRB1 genotype frequencies were significantly deviated from Hardy-Weinberg equilibrium, while HLA-DQB1 frequencies showed no deviation. A*03, B*35, DRB1*11 and DQB1*02 were the most frequent allele groups, while A*02-B*07-DRB1*04-DQB1*03 was the most frequent haplotype. HLA data are available in the Allele Frequencies Net Database (AFND: 3680) under the population name "Iraq Arabs".

中文翻译：

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伊拉克阿拉伯人中的HLA-A，-B，-DRB1和-DQB1多态性。

在本报告中，在149个无关的伊拉克阿拉伯潜在的骨髓和肾脏供体中确定了HLA多态性（A，B，DRB1和DQB1位点）。分子基因分型是通过聚合酶链反应，然后进行特异性寡核苷酸探针杂交来进行的。通过Arlequin软件分析数据。HLA-A，-B和-DRB1基因型频率显着偏离Hardy-Weinberg平衡，而HLA-DQB1基因型频率未显示偏差。A * 03，B * 35，DRB1 * 11和DQB1 * 02是最常见的等位基因组，而A * 02-B * 07-DRB1 * 04-DQB1 * 03是最常见的单倍型。HLA数据可在等位基因频率数据库（AFND：3680）中以“伊拉克阿拉伯人”的名字获得。