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A review of fabrication polymer scaffolds for biomedical applications using additive manufacturing techniques
Biocybernetics and Biomedical Engineering ( IF 5.3 ) Pub Date : 2020-02-20 , DOI: 10.1016/j.bbe.2020.01.015
Patrycja Szymczyk-Ziółkowska , Magdalena Beata Łabowska , Jerzy Detyna , Izabela Michalak , Piotr Gruber

This paper presents the current state-of-the art of additive manufacturing (AM) applications in the biomedical field, especially in tissue engineering. Multiple advantages of additive manufacturing allow to precise three-dimensional objects fabrication with complex structure using various materials. Depending on the purpose of the manufactured part, different AM technologies are implemented, in which a specific material can be utilized. In the biomedical field, there are used several techniques such as: Binder Jetting, Material Extrusion, Material Jetting, Powder Bed Fusion, Sheet Lamination, Vat Polymerization. This article focuses on the utilization of polymer materials (natural and synthetic) taking into account hydrogels in scaffolds fabrication. Assessment of polymer scaffolds mechanical properties enables personalized patient care, as well as prevents damage after implantation in human body. By controlling process parameters it is possible to obtain optimised mechanical properties of manufactured parts.



中文翻译:

使用增材制造技术的生物医学应用聚合物支架的综述

本文介绍了生物医学领域,尤其是组织工程领域中增材制造(AM)应用的最新技术。增材制造的多重优势允许使用各种材料以复杂的结构精确地制造三维物体。取决于制造零件的目的,实施了不同的增材制造技术,其中可以使用特定的材料。在生物医学领域,使用了多种技术,例如:粘合剂喷射,材料挤出,材料喷射,粉末床熔合,片层合,槽聚合。本文重点研究聚合物材料(天然和合成)的利用,并考虑到支架制造中的水凝胶。评估聚合物支架的机械性能可实现个性化的患者护理,以及防止植入人体后的损坏。通过控制工艺参数,可以获得所制造零件的最佳机械性能。

更新日期:2020-02-20
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