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Experimental and numerical flow analysis through arteries with stent using particle image velocimetry and computational fluid dynamics method
Biocybernetics and Biomedical Engineering ( IF 5.3 ) Pub Date : 2020-03-28 , DOI: 10.1016/j.bbe.2020.02.010
Michał Tomaszewski , Kamil Sybilski , Paweł Baranowski , Jerzy Małachowski

In the paper, an experimental and numerical flow through various kind of arteries is considered. The flow analyses are carried out on the research set up using Particle Image Velocimetry Method (PIV). The individual components of the research set up are discussed and the measurement methodology is explained. The work consists of two parts. The first one is focused on modelling numerical simulation of the stent installation procedure using an expandable balloon and the flow domain design methodology is described. In the final part, an experimental flow test on an artificial silicone vessel (diameter 3.2 mm) with a stent is performed. The results of the experimental tests are compared with a corresponding numerical simulation. The paper presents numerical simulation for two different flow domains and the results obtained from the experimental tests. In both, the experimental tests and numerical simulation, the pulsatile time dependent flow and pressure characteristic are used. Hemodynamic parameters such as the time average wall shear stress (TAWSS) and velocity vector distribution are analysed. The flow was studied at four Reynolds number values (1223; 2257; 3198; 3762) for the straight vessel and at two values for the vessel containing a stent (1223, 2257). A diameter of the vessel was 3.2 mm. Pulsating blood flow based on the data from the experimental test was analysed. During the numerical simulation it was verified which regions of the vessel had TAWSS values below 0.4 Pa. A satisfactory correlation between outcomes of the numerical simulation and the experimental test was obtained. The flow analysis is conducted in ANSYS Fluent software. Additionally, the methodology for defining the velocity profile at the entrance is presented, in order to form the velocity profile in the first step of analysed cases. The study shows possibility to create a new research set up capable of testing various clinical cases of varying pressure values in the setup, or testing the effects of vessel geometrical changes, which allows observing an influence of those parameters on the fluid flow characteristic. As the analysis for the stent has shown, the regions of low TAWSS values are located in a close proximity to the stent struts.



中文翻译:

使用粒子图像测速法和计算流体力学方法的带有支架的动脉的实验和数值流分析

在本文中,考虑了通过各种动脉的实验和数值流。流量分析是在使用粒子图像测速法(PIV)建立的研究中进行的。讨论了研究设置的各个组成部分,并说明了测量方法。这项工作包括两个部分。第一个重点是使用可膨胀球囊对支架安装过程的数值模拟进行建模,并介绍了流域设计方法。在最后一部分中,对带有支架的人造硅胶容器(直径3.2毫米)进行了实验流量测试。将实验测试的结果与相应的数值模拟进行比较。本文介绍了两种不同流动域的数值模拟,以及从实验测试中获得的结果。在实验测试和数值模拟中,都使用了随时间变化的脉动流量和压力特性。分析了时间平均壁切应力(TAWSS)和速度矢量分布等血液动力学参数。对于直管,在四个雷诺数值(1223; 2257; 3198; 3762)下对流量进行了研究,对于包含支架的血管(1223,2257),在两个值下进行了研究。容器的直径为3.2mm。基于来自实验测试的数据分析脉动血流。在数值模拟过程中,验证了容器的哪些区域的TAWSS值低于0.4 Pa。数值模拟结果与实验测试之间具有令人满意的相关性。流量分析在ANSYS Fluent软件中进行。另外,提出了在入口处定义速度分布的方法,以便在分析案例的第一步中形成速度分布。这项研究表明有可能建立一个新的研究机构,该机构能够测试设置中压力值变化的各种临床病例,或者测试血管几何形状的变化,从而观察这些参数对流体流动特性的影响。正如对支架的分析所显示的,TAWSS值低的区域非常靠近支架撑杆。或测试容器几何形状变化的影响,从而可以观察那些参数对流体流动特性的影响。正如对支架的分析所显示的,TAWSS值低的区域非常靠近支架撑杆。或测试容器几何形状变化的影响,从而可以观察那些参数对流体流动特性的影响。正如对支架的分析所显示的,TAWSS值低的区域非常靠近支架撑杆。

更新日期:2020-03-28
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