As a non-destructive and label-free detection technology, surface-enhanced Raman scattering (SERS) has been widely used in environmental-pollutant detection, biological-tissue sensing, molecular fingerprint analysis, and so on. Herein, we report an active SERS material, namely quasi-metallic WO₂ nanodendrites. Due to the dual boosts of electromagnetic mechanism (EM) enhancement and chemical mechanism (CM) enhancement, the WO₂ nanodendrites achieve an 8.5 × 10⁷ level enhanced factor and a 10⁻¹⁰ level detection limit for probe molecules. The experimental and theoretical results demonstrate that the performance comes from the dual enhancement of the highly efficient interface charge transfer and the vigorous surface plasma resonance (SPR) of the quasi-metals. Furthermore, these WO₂ nanodendrites show high chemical stability, are resistant to long-term air oxidation, and even can endure strong acid and alkali corrosion without reducing their SERS activity. The separation and detection of multicomponent samples are achieved simultaneously when these nanodendrites are fabricated into patterned SERS chips.

作为一种无损，无标记的检测技术，表面增强拉曼散射（SERS）已广泛用于环境污染物检测，生物组织传感，分子指纹分析等。在这里，我们报道了一种活性SERS材料，即准金属WO ₂纳米树枝状晶体。由于电磁机制（EM）增强和化学机制（CM）增强的双重推动，WO ₂纳米树枝晶的增强因子达到8.5×10 ^7，而增强因子达到10 ^-10探针分子的水平检测极限。实验和理论结果表明，该性能来自高效界面电荷转移和准金属的剧烈表面等离子体共振（SPR）的双重增强。此外，这些WO ₂纳米树枝晶显示出高化学稳定性，耐长期空气氧化，甚至可以承受强酸和强碱腐蚀而不会降低其SERS活性。将这些纳米树枝晶制成图案化的SERS芯片时，可以同时实现多组分样品的分离和检测。