Objectives

The aim of this study was to evaluate patients’ self-reported adherence to dual antiplatelet therapy (DAPT) and determine the factors associated with premature discontinuation of DAPT.

Methods

The cross-sectional interview-based study was conducted among adult outpatients who visited the outpatient department of King Khalid University Hospital, Cardiac Center in Riyadh, Saudi Arabia, over a period of 3 months from May to July of 2016. Medication adherence was assessed using the Self-efficacy for Appropriate Medication Use Scale (SEAMS), which is composed of 13 items with a 3-point Likert scale.

Results

A total of 192 patients participated in the study. The majority of the participants were male (82.1%), and the mean age was 55.66 ± 10.80 years. More than 84% (84.4%) of the patients reported that they were “confident” in taking several medications each day. The minimum and maximum SEAMS scores were 22 and 39, respectively, with the mean score being 30.8 ± 3.5. Almost all patients had moderate scores and adherence; only one patient got a score of 39. Among sociodemographic characteristics, only health insurance and income were significantly associated with the medication adherence score (p < 0.05).

Conclusions

Study results concluded that patients had a moderate level of adherence towards DAPT in Saudi Arabia, however Patient education on DAPT is essential to improve adherence to medication treatment. More effective intentions and education methods should be developed to improve long-term DAPT adherence.

中文翻译：

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急性冠状动脉综合征患者坚持预防性双重抗血小板治疗——在沙特大学医院进行的一项研究

目标

本研究的目的是评估患者自我报告的双联抗血小板治疗 (DAPT) 依从性，并确定与过早停用 DAPT 相关的因素。

方法

这项基于横断面访谈的研究是在 2016 年 5 月至 7 月的 3 个月内访问沙特阿拉伯利雅得哈立德国王大学医院心脏中心门诊部的成人门诊患者中进行的。药物依从性评估使用适当用药的自我效能感量表（SEAMS），由 13 个条目组成，采用李克特 3 点量表。

结果

共有 192 名患者参与了这项研究。大多数参与者是男性（82.1%），平均年龄为 55.66 ± 10.80 岁。超过 84% (84.4%) 的患者报告说他们“有信心”每天服用几种药物。最低和最高 SEAMS 分数分别为 22 和 39，平均分数为 30.8 ± 3.5。几乎所有患者的评分和依从性均中等；只有一名患者的得分为 39。在社会人口学特征中，只有健康保险和收入与服药依从性得分显着相关（p < 0.05）。

结论

研究结果得出结论，沙特阿拉伯患者对 DAPT 的依从性中等，但对患者进行 DAPT 教育对于提高药物治疗的依从性至关重要。应开发更有效的意图和教育方法，以提高长期 DAPT 依从性。