Abstract A novel voltammetric method was developed for the sensitive determination of chlorogenic acid (CGA) using a glassy carbon electrode (GCE) modified with niobium nanoparticles (NbNPs) and multiwalled carbon nanotubes (CNTs). The analytical techniques such as energy dispersive X-ray analysis (EDX), scanning electron microscopy (SEM) and X-ray diffraction spectroscopy were used for characterizing electrode material. The proposed voltammetric platform exhibited a highly improved redox couple for CGA. The peak separations (ΔEp) for CGA were 27 mV, 10 mV and 0 mV on the surface of unmodified GCE, CNTs/GCE and NbNPs/CNTs/GCE, respectively. Such a remarkable decrease in the value of ΔEp at NbNPs/CNTs/GCE showed that the electrode process of CGA has been accelerated at the proposed platform. In addition, a potential difference (ΔEp) of 0 V observed at the surface of proposed electrochemical platform was a clear indication of the occurrence of a symmetric voltammogram which could be attributed to a fully surface behavior of CGA. In addition, the current responses of CGA versus concentrations were linear in the range of 2.0 × 10−9 ~ 2.0 × 10−6 M with a detection limit of 8.2 × 10−10 M. Sensitive detection of CGA in samples is of importance for both scientific and therapeutic reasons due to its potential use for the treatment in many diseases. Therefore, the proposed voltammetric method at NbNPs/CNTs/GCE was applied to food samples.

中文翻译：

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基于碳纳米管-铌纳米颗粒测定绿原酸的新型伏安传感平台

摘要 开发了一种使用铌纳米粒子 (NbNPs) 和多壁碳纳米管 (CNTs) 修饰的玻碳电极 (GCE) 灵敏测定绿原酸 (CGA) 的新型伏安法。使用能量色散 X 射线分析 (EDX)、扫描电子显微镜 (SEM) 和 X 射线衍射光谱等分析技术来表征电极材料。所提出的伏安法平台展示了高度改进的 CGA 氧化还原对。在未改性 GCE、CNTs/GCE 和 NbNPs/CNTs/GCE 表面上，CGA 的峰分离 (ΔEp) 分别为 27 mV、10 mV 和 0 mV。NbNPs/CNTs/GCE 上 ΔEp 值的显着下降表明 CGA 的电极过程在所提出的平台上得到了加速。此外，在提出的电化学平台表面观察到的 0 V 电位差 (ΔEp) 清楚地表明对称伏安图的出现，这可归因于 CGA 的完全表面行为。此外，CGA 对浓度的电流响应在 2.0 × 10−9 ~ 2.0 × 10−6 M 范围内呈线性，检测限为 8.2 × 10−10 M。样品中 CGA 的灵敏检测对于科学和治疗方面的原因，因为它可能用于治疗许多疾病。因此，建议的 NbNPs/CNTs/GCE 伏安法适用于食品样品。CGA 与浓度的当前响应在 2.0 × 10−9 ~ 2.0 × 10−6 M 范围内呈线性，检测限为 8.2 × 10−10 M。样品中 CGA 的灵敏检测对于科学和治疗原因，因为它可能用于治疗许多疾病。因此，建议的 NbNPs/CNTs/GCE 伏安法适用于食品样品。CGA 与浓度的当前响应在 2.0 × 10−9 ~ 2.0 × 10−6 M 范围内呈线性，检测限为 8.2 × 10−10 M。样品中 CGA 的灵敏检测对于科学和治疗原因，因为它可能用于治疗许多疾病。因此，建议的 NbNPs/CNTs/GCE 伏安法适用于食品样品。