Brain diseases including Alzheimer’s, Parkinson’s, Huntington’s and brain tumours are globally challenging issues. While therapeutics has been significantly developed for the treatment, recent nanotechnology emerges as a potent tool to deliver therapeutics to brain. Among others, nanoparticle (NP)-mediated drug delivery has been considered promising because the NP can be tailored to target the receptors expressed on cells while incorporating and releasing the therapeutic molecules in a controlled manner.^1–4

中文翻译：

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纳米粒子靶向治疗脑疾病

包括阿尔茨海默氏症，帕金森氏症，亨廷顿氏症和脑肿瘤在内的脑病是全球具有挑战性的问题。尽管已经为治疗方法开发了重要的治疗方法，但近来的纳米技术应运而生，成为将治疗剂输送至大脑的有效工具。其中，认为纳米颗粒（NP）介导的药物递送是有前途的，因为可以定制NP以靶向细胞上表达的受体，同时以受控方式掺入和释放治疗分子。^1–4