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Molecular dissection of pheromone selectivity in the competence signaling system ComRS of streptococci [Biochemistry]
Proceedings of the National Academy of Sciences of the United States of America ( IF 11.1 ) Pub Date : 2020-04-07
Laura Ledesma–Garcia, Jordhan Thuillier, Armando Guzman–Espinola, Imke Ensinck, Ines Li de la Sierra–Gallay, Noureddine Lazar, Magali Aumont–Nicaise, Johann Mignolet, Patrice Soumillion, Sylvie Nessler, Pascal Hols

Competence allows bacteria to internalize exogenous DNA fragments for the acquisition of new phenotypes such as antibiotic resistance or virulence traits. In most streptococci, competence is regulated by ComRS signaling, a system based on the mature ComS pheromone (XIP), which is internalized to activate the (R)RNPP-type ComR sensor by triggering...

中文翻译:

链球菌能力信号系统ComRS中信息素选择性的分子解剖学[生物化学]

竞争能力使细菌能够内化外源DNA片段,以获取新的表型,例如抗生素抗性或毒力特性。在大多数链球菌中,胜任力是由ComRS信号调节的,ComRS信号是基于成熟的ComS信息素(XIP)的系统,该系统可以通过触发...来激活(R)RNPP型ComR传感器。
更新日期:2020-04-08
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