Hsp70 is a conserved molecular chaperone that plays an indispensable role in regulating protein folding, translocation, and degradation. The conformational dynamics of Hsp70 and its regulation by cochaperones are vital to its function. Using bulk and single-molecule fluorescence resonance energy transfer (smFRET) techniques, we studied the interdomain conformational distribution of...

中文翻译：

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Hsp70构象循环的动力学揭示了Hsp70动态和异构性质对其功能的重要性[生物物理学和计算生物学]

Hsp70是一种保守的分子伴侣，在调节蛋白质折叠，转运和降解中起着不可或缺的作用。Hsp70的构象动力学及其伴侣蛋白的调节对其功能至关重要。使用本体和单分子荧光共振能量转移（smFRET）技术，我们研究了...的域间构象分布。