Mounting experimental evidence suggests a role for the spatial organization of chromatin in crucial processes of the cell nucleus such as transcription regulation. Chromosome conformation capture techniques allow us to characterize chromatin structure by mapping contacts between chromosomal loci on a genome-wide scale. The most widespread modality is to measure...

中文翻译：

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由群体平均联系数据得出的染色质结构的贝叶斯推断[生物物理学与计算生物学]

越来越多的实验证据表明，染色质的空间组织在细胞核的关键过程（例如转录调控）中发挥着作用。染色体构象捕获技术使我们能够通过在全基因组范围内绘制染色体基因座之间的接触来表征染色质结构。最普遍的方式是测量...