Metagenomics studies leverage genomic reference databases to generate discoveries in basic science and translational research. However, current microbial studies use disparate reference databases that lack consistent standards of specimen inclusion, data preparation, taxon labelling and accessibility, hindering their quality and comprehensiveness, and calling for the establishment of recommendations for reference genome database assembly. Here, we analyze existing fungal and bacterial databases and discuss guidelines for the development of a master reference database that promises to improve the quality and quantity of omics research.

中文翻译：

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改善微生物数据库的可用性和全面性。

元基因组学研究利用基因组参考数据库在基础科学和转化研究中产生发现。但是，当前的微生物研究使用的参考数据库不同，缺乏一致的标本包含，数据制备，分类单元标签和可及性标准，阻碍了它们的质量和全面性，并呼吁建立参考基因组数据库组装的建议。在这里，我们分析了现有的真菌和细菌数据库，并讨论了开发主要参考数据库的指南，该数据库有望提高组学研究的质量和数量。