Coronavirus Disease 2019 (COVID‐19) has become a pandemic since March 2020. We describe here 2 cases of COVID‐19 infection in a posttransplant setting. First one is a 59‐year‐old renal transplant recipient; the second is a 51‐year‐old allogeneic bone marrow transplant recipient. Both patients were on immunosuppressant therapy and had stable graft function before COVID‐19 infection. After the diagnosis of COVID‐19, immunosuppressive agents were discontinued and methylprednisolone with prophylactic antibiotics were initiated, however, the lung injury progressed. The T cells were extremely low in both patients after infection. Both patients died despite the maximal mechanical ventilatory support. Therefore, the prognosis of COVID‐19 pneumonia following transplantation is not optimistic and remains guarded. Lower T cell count may be a surrogate for poor outcome.

中文翻译：

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移植后患者中的 COVID-19——2 例报告。

自 2020 年 3 月以来，2019 年冠状病毒病 (COVID-19) 已成为大流行病。我们在此描述了 2 例移植后环境中的 COVID-19 感染病例。第一个是 59 岁的肾移植受者；第二个是 51 岁的同种异体骨髓移植受者。两名患者都在接受免疫抑制治疗，并且在 COVID-19 感染之前具有稳定的移植物功能。诊断出 COVID-19 后，停用免疫抑制剂并开始使用甲基强的松龙和预防性抗生素，但肺损伤进展。感染后两名患者的 T 细胞极低。尽管有最大的机械通气支持，但两名患者均死亡。因此，移植后COVID-19肺炎的预后不容乐观，仍需谨慎。