Benzothiazoles have played an important role in the field of biochemistry and medicinal chemistry due to their highly pharmaceutical and biological activity. The development of synthetic processes is undoubtedly one of the most significant problems facing researchers. In this review paper, we provided recent advances in the synthesis of benzothiazole compounds related to green chemistry from condensation of 2-aminobenzenethiol with aldehydes/ketones/acids/acyl chlorides and the cyclization of thioamide or carbon dioxide (CO2) as raw materials, and the future development trend and prospect of the synthesis of benzothiazoles were anticipated.

中文翻译：

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绿色化学相关苯并噻唑类化合物的合成研究新进展


苯并噻唑类化合物因其高度的药物和生物活性而在生物化学和药物化学领域发挥着重要作用。合成工艺的发展无疑是研究人员面临的最重要的问题之一。在这篇综述论文中，我们介绍了以2-氨基苯硫醇与醛/酮/酸/酰氯缩合以及硫代酰胺或二氧化碳（CO2）为原料环合合成绿色化学相关苯并噻唑类化合物的最新进展，以及对苯并噻唑合成的未来发展趋势和前景进行了展望。