The aim of this study was to compare quilting suture with conventional suture on the formation of seroma at pectoral area after mastectomy (ME) with sentinel lymph nodes biopsy (SLN) or axillary lymph nodes dissection (ALND) for breast cancer. Two hundred thirty-five consecutive breast cancer patients were retrospectively analyzed. The primary outcome was the incidence of Grade 2 or Grade 3 seroma at anterior pectoral area within 1 month postoperatively. We categorized seroma into early or late seroma according to the drainage removal time. Cox regression was used for analysis. The incidence of Grade 2 and 3 seroma was significantly higher in the conventional suture group compared with that in the quilting suture group (19.3% vs. 9.5%, p = 0.032), which was attributed to the late seroma in Grade 2 and 3. Quilting suture was associated with longer time for fixing flaps compared with that of conventional suture (504.7 s vs. 109.1 s, p < 0.001), but with less volume of drainage. Old age, high body mass index and conventional suture were independently risk factors for Grade 2 and 3 seroma. Quilting suture decreased the incidence of Grade 2 and 3 seroma at pectoral area within 1 month after mastectomy, especially the late seroma in Grade 2 and 3.

中文翻译：

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preventing缝缝合术比常规带引流术的缝合术更好，可防止乳房切除术后在胸腔区域形成血清肿。

这项研究的目的是比较割术和常规缝合在乳腺癌切除术（ME）和前哨淋巴结活检（SLN）或腋窝淋巴结清扫术（ALND）后胸腺区域的血清肿形成的比较。回顾性分析了235例连续性乳腺癌患者。主要结局是术后1个月内前胸区2级或3级血清肿的发生率。我们根据引流清除时间将血清肿分为早期或晚期血清肿。使用Cox回归进行分析。常规缝线组中2级和3级血清的发生率比缝线组高得多（19.3％vs.9.5％，p = 0.032），这归因于2级和3级血清的晚期。与常规缝合相比，缝缝合与固定皮瓣所需的时间更长（504.7 s对109.1 s，p <0.001），但引流量较少。老年，高体重指数和常规缝合是2级和3级血清肿的独立危险因素。mast缝缝合降低了乳房切除术后1个月内胸区域2级和3级血清肿的发生率，尤其是2级和3级晚期血清肿。