Mechanistic Insights for Optimizing PSMA Radioligand Therapy.,Clinical Cancer Research

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Mechanistic Insights for Optimizing PSMA Radioligand Therapy.
Clinical Cancer Research ( IF 11.5 ) Pub Date : 2020-06-15 , DOI: 10.1158/1078-0432.ccr-20-0209
Aravind S Ravi Kumar _{1,

2} , Michael S Hofman _{1,

2}

Affiliation

PSMA radioligand therapy is a promising new class of therapy for prostate cancer. Heterogeneity of PSMA expression is an important factor explaining variability in clinical results. The ability to visualize the target with theranostics provides unique mechanistic insights. Potential clinically applicable strategies to improve patient selection and optimize therapeutic efficacy are discussed. See related article by Current et al., [p. 2946][1] [1]: /lookup/volpage/26/2946?iss=12

中文翻译：

优化PSMA放射配体疗法的机理见解。

PSMA放射配体疗法是一种有前途的前列腺癌新疗法。PSMA表达的异质性是解释临床结果变异性的重要因素。用诊断学可视化目标的能力提供了独特的机械洞察力。讨论了改善患者选择和优化治疗效果的潜在临床适用策略。参见Current等人的相关文章，[第 2946] [1] [1]：/ lookup / volpage / 26/2946？iss = 12

更新日期：2020-06-15

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