A lobular capillary hemangioma, previously known as a pyogenic granuloma, is a benign vascular lesion of the skin or mucous membrane. We report a case of capillary hemangioma of lobular subtype in the calvarium of a 28-year-old pregnant woman which presented as a sore and rapidly growing bulge over the left fronto-parietal region. Magnetic resonance imaging of the brain and skull showed an expansive tumor with brain displacement, skull erosion, and scalp infiltration. The tumor was surgically removed, and histopathological examination showed a capillary hemangioma of lobular subtype. To the best of our knowledge, this is the first report of a lobular capillary hemangioma in the calvarium, and it represents a rarity to be considered among the many other differential diagnoses for neurosurgical lesions involving the skull, especially in pregnant women.

小叶性毛细血管瘤，以前称为化脓性肉芽肿，是皮肤或粘膜的良性血管病变。我们报告了一例28岁孕妇的颅骨小叶亚型毛细血管瘤的病例，表现为左额顶叶区域酸痛且迅速增长。脑部和颅骨的磁共振成像显示肿大的肿瘤伴有脑移位，颅骨侵蚀和头皮浸润。手术切除肿瘤，组织病理学检查显示为小叶亚型毛细血管瘤。据我们所知，这是颅骨小叶性毛细血管瘤的首次报道，在涉及颅骨的神经外科病变的许多其他鉴别诊断中，这是罕见的。