Rapid methods for diagnosis of bacterial infections are urgently needed to reduce inappropriate use of antibiotics, which contributes to antimicrobial resistance. In many rapid diagnostic methods, DNA oligonucleotide probes, attached to a surface, bind to specific nucleotide sequences in the DNA of a target pathogen. Typically, each probe binds to...

中文翻译：

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通过多价结合检测细菌基因组的探针的计算设计[生物物理学和计算生物学]

迫切需要快速诊断细菌感染的方法，以减少不当使用抗生素的情况，这会增加抗菌素的耐药性。在许多快速诊断方法中，附着在表面的DNA寡核苷酸探针与靶病原体DNA中的特定核苷酸序列结合。通常，每个探针都结合...