当前位置: X-MOL 学术Proc. Natl. Acad. Sci. U.S.A. › 论文详情
Our official English website, www.x-mol.net, welcomes your feedback! (Note: you will need to create a separate account there.)
Squalene and cholesterol in the balance at the ER membrane [Commentaries]
Proceedings of the National Academy of Sciences of the United States of America ( IF 9.4 ) Pub Date : 2020-04-01
James A. Nathan

Targeting the cholesterol biosynthetic pathway has become a mainstay for the treatment of ischemic heart disease (1). However, the importance of cholesterol metabolism is not just confined to atherosclerosis, as cholesterol is an essential component of membranes, a precursor for other metabolic pathways, and can fuel tumor growth (2). Understanding...

中文翻译:

角鲨烯和胆固醇在ER膜上处于平衡状态[评论]

靶向胆固醇的生物合成途径已成为治疗缺血性心脏病的主要手段(1)。然而,胆固醇代谢的重要性不仅限于动脉粥样硬化,因为胆固醇是膜的重要组成部分,是其他代谢途径的前体,并且可以促进肿瘤生长(2)。理解...
更新日期:2020-04-03
down
wechat
bug