The synthesis of a series of thiosemicarbazone ligands bearing azido groups, which were further immobilized on the surface of phenylethynyl-functionalized glassy carbon (GC) electrodes through a Cu(I)-catalyzed "click" reaction is reported. The modified electrodes presented a remarkable selectivity towards Hg(II) among other metal ions. Under optimized conditions and using the accumulation at open circuit-anodic stripping technique, detection limits below nanomolar level were obtained for Hg(II). Further, we demonstrated that GC electrodes "clicked" with thiosemicarbazone ligands can be used successfully for the analysis of Hg(II) ions from water samples. Moreover, the modified electrodes showed a very good reproducibility, stability over time and reusability, and can therefore be employed as sensitive and selective sensors for Hg(II) ion analysis in environmental samples.

报道了一系列带有叠氮基的硫代半脲配体的合成，这些配体通过Cu（I）催化的“点击”反应进一步固定在苯基乙炔基官能化的玻碳（GC）电极的表面上。改性电极对其他金属离子具有显着的Hg（II）选择性。在最佳条件下，并利用开路阳极剥离技术中的累积量，获得了汞（II）低于纳摩尔水平的检测限。此外，我们证明了用硫代半脲配体“点击”的GC电极可以成功地用于分析水样中的Hg（II）离子。此外，改性电极显示出非常好的重现性，随时间变化的稳定性和可重复使用性，