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Gastruloids Gain Muscle: Somite Formation in Embryo-Like Structures
Cell Stem Cell ( IF 19.8 ) Pub Date : 2020-04-02 , DOI: 10.1016/j.stem.2020.03.011 Edwin A. Rosado-Olivieri , Ali H. Brivanlou
中文翻译:
胃类肌获得肌肉:胚状结构中的松节形成。
更新日期:2020-04-20
Cell Stem Cell ( IF 19.8 ) Pub Date : 2020-04-02 , DOI: 10.1016/j.stem.2020.03.011 Edwin A. Rosado-Olivieri , Ali H. Brivanlou
Gastruloids are embryo-like structures that display key features of post-implantation embryonic development, yet whether they fully recapitulate in vivo embryogenesis remains unsolved. Recently in Nature, van den Brink et al. (2020) performed high-resolution gene expression analysis to identify significant similarities between mouse gastruloids and embryos in positional lineage segregation and somite formation.
中文翻译:
胃类肌获得肌肉:胚状结构中的松节形成。
胚状体是类胚胎结构,显示出植入后胚胎发育的关键特征,但它们是否能完全概括体内胚胎发生仍未解决。最近,在《自然》杂志上,van den Brink等人 (2020)进行了高分辨率的基因表达分析,以发现小鼠类胚体和胚胎之间的位置谱系分离和体节形成的显着相似性。