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Islet-Resident Endocrine Progenitors: A New Hope for Beta Cell PROCReation?
Cell Stem Cell ( IF 19.8 ) Pub Date : 2020-04-02 , DOI: 10.1016/j.stem.2020.03.008
Paraish S. Misra , M. Cristina Nostro

The existence of an endocrine progenitor in the adult mouse pancreas has been controversial. Recently in Cell, Wang et al. (2020) use the cell-surface marker Procr to define a population of cells within the adult islet of Langerhans that is capable of generating all endocrine cells and is amenable to in vitro expansion.



中文翻译:

胰岛驻留的内分泌祖细胞:β细胞繁殖的新希望?

在成年小鼠胰腺中内分泌祖细胞的存在一直存在争议。最近在Cell中,Wang等人。(2020年)使用细胞表面标记Procr定义朗格汉斯成年胰岛内的细胞群,该细胞群能够产生所有内分泌细胞,并适于体外扩增。

更新日期:2020-04-20
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