Air pollution has been with humankind throughout evolution (e.g. volcanoes, forest fires), but it rapidly accelerated with the industrial revolution. Although the history of London's suffocating fogs began in the 18th century with coal power, it was the acute London fog episode of December 1952, and similar crises, that galvanised public health officials to begin to address the problem. The tremendous growth of automobiles reliant on internal combustion engines during the latter half of the 20th century ultimately led to current concerns with traffic-related air pollution (TRAP), causing researchers to seek a better understanding of air pollution health effects [1, 2]. There are many challenges in interpretation of novel assays for health effects in human challenge studies https://bit.ly/3bdF5me

中文翻译：

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NETs：一种与交通相关的空气污染暴露的新生物标志物：他们准备好捕鱼了吗？

空气污染在整个进化过程中一直伴随着人类（例如火山、森林大火），但随着工业革命而迅速加速。尽管伦敦令人窒息的大雾的历史始于 18 世纪的煤电，但正是 1952 年 12 月的严重伦敦大雾事件和类似的危机促使公共卫生官员开始着手解决这个问题。20 世纪下半叶，依赖内燃机的汽车数量激增，最终引发了当前对交通相关空气污染 (TRAP) 的担忧，促使研究人员寻求更好地了解空气污染对健康的影响 [1, 2] . 在人类挑战研究 https://bit.ly/3bdF5me 中解释新的健康影响分析方法存在许多挑战