![][1] Caspase-8 is a key apoptotic mediator and its expression is lost in many tumor types. Paradoxically, caspase-8 is highly expressed in a subset of tumors. Müller and colleagues identified a novel prosurvival function for nuclear caspase-8 that facilitates bypass of a p53-

中文翻译：

---

近期癌症文献集锦


！[] [1] Caspase-8是关键的细胞凋亡介体，其表达在许多类型的肿瘤中均丢失。矛盾的是，caspase-8在肿瘤的一个子集中高度表达。Müller及其同事确定了一种新的核caspase-8生存功能，该功能有助于绕过p53-