INTRODUCTION Measles is highly contagious, but preventable viral disease. Its outbreaks appear all over the world, and decreasing herd immunity excludes its elimination. High levels of IgG antibodies against a virus efficiently protects against infection. AIM OF THIS STUDY To assess the seroprevalence of anti-measles IgG in the serum of patients at different age levels tested for measles IgG at our laboratory. MATERIAL AND METHODS The study was conducted from March to June of 2019. Retrospective analysis included results for measles-specific IgG from 364 tested patients. The age of enrolled subjects ranged from four months to 101 years, with a median age of 46, and a mean age of 43 ±18. Quantification of anti-measles IgG was performed using indirect chemiluminescence immunoassays on the DiaSorin Liaison® automated analyzer. RESULTS Our results showed a seropositivity ratio of 78.02%. The lowest number of seropositive subjects was in the group of infants (0-1 years old), with a ratio of 53.85%, and the group of adults of 19-38 years old at 55.68%. The group of the oldest patients (70-101 years old) had the highest ratio of seropositive subjects (100%), while adults of 60-69 years old had a seropositivity ratio of 97.22%. CONCLUSIONS These data suggest that the group of young adults who were vaccinated with one or two doses of MMR vaccine in childhood are the most susceptible for infection, and when working in contact with other people, should be re-vaccinated for protection against measles.

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在选定的波兰人群中针对麻疹的 IgG 抗体的血清阳性率 - 我们是否需要重新接种疫苗？

引言 麻疹是高度传染性但可预防的病毒性疾病。它的爆发出现在世界各地，群体免疫力的下降排除了它的消除。高水平的抗病毒 IgG 抗体可有效防止感染。本研究的目的 评估在我们实验室进行麻疹 IgG 检测的不同年龄水平患者血清中抗麻疹 IgG 的血清阳性率。材料和方法该研究于 2019 年 3 月至 6 月进行。回顾性分析包括来自 364 名测试患者的麻疹特异性 IgG 结果。入组受试者的年龄从 4 个月到 101 岁不等，中位年龄为 46 岁，平均年龄为 43 ± 18 岁。在 DiaSorin Liaison® 自动分析仪上使用间接化学发光免疫测定法进行抗麻疹 IgG 的定量。结果 我们的结果显示血清阳性率为 78.02%。血清阳性受试者人数最少的是婴儿组（0-1岁），比例为53.85%，19-38岁的成年人组为55.68%。年龄最大的患者组（70-101 岁）血清阳性率最高（100%），而 60-69 岁的成年人血清阳性率为 97.22%。结论 这些数据表明，在儿童时期接种过一剂或两剂 MMR 疫苗的年轻人群最容易感染，当与他人接触时，应重新接种以预防麻疹。19-38岁的成年人组占55.68%。年龄最大的患者组（70-101 岁）血清阳性率最高（100%），而 60-69 岁的成年人血清阳性率为 97.22%。结论 这些数据表明，在儿童时期接种过一剂或两剂 MMR 疫苗的年轻人群最容易感染，当与他人接触时，应重新接种以预防麻疹。19-38岁的成年人组占55.68%。年龄最大的患者组（70-101 岁）血清阳性率最高（100%），而 60-69 岁的成年人血清阳性率为 97.22%。结论 这些数据表明，在儿童时期接种过一剂或两剂 MMR 疫苗的年轻人群最容易感染，当与他人接触时，应重新接种以预防麻疹。