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Tragacanth-mediate synthesis of NiO nanosheets for cytotoxicity and photocatalytic degradation of organic dyes.
Bioprocess and Biosystems Engineering ( IF 3.5 ) Pub Date : 2020-03-06 , DOI: 10.1007/s00449-020-02315-7
Zahra Sabouri 1, 2 , Alireza Akbari 2 , Hasan Ali Hosseini 2 , Mehrdad Khatami 3 , Majid Darroudi 4, 5
Affiliation  

In this study, NiO nanosheets have been manufactured using a co-precipitation approach that involved the usage of nickel nitrate (Ni (NO3)2.6H2O) as the raw material and tragacanth in the role of a stabilizing agent. NiO nanosheets have been fabricated through the reduction of nickel nitrate solution that had been obtained by the application of aqueous extract of tragacanth, which is capable of functioning as a reducing and stabilizing agent. In the following, the physical and chemical properties of tragacanth-stabilized NiO nanosheets have been identified via FESEM, EDS, XRD, UV-Vis, and FT-IR techniques. According to the XRD pattern, these particular nanosheets have contained a cubic structure and group space Fm3m, along with the average size of about 18 to 43 nm that had been in agreement with the FESEM measurements. In addition, we have evaluated the photocatalytic activity of tragacanth-stabilized NiO nanosheets on the degradations of methylene blue (MB) and methyl orange (MO) dyes. The performed photocatalytic assessment has displayed that the nanosheets can degrade 82% of MO within 210 min and 60% of MB in 300 min. The cytotoxicity of tragacanth-stabilized NiO nanosheets on human Glioblastoma cancer (U87MG) cell lines has been investigated via the MTT assay, while it has been detected in the obtained results that the inhibitory concentration (IC50) had been 125 µg/mL.

中文翻译:

黄胶介导的NiO纳米片的合成对细胞毒性和有机染料的光催化降解。

在这项研究中,使用共沉淀法制造了NiO纳米片,该共沉淀法涉及使用硝酸镍(Ni(NO3)2.6H2O)作为原料和黄aga胶作为稳定剂的作用。NiO纳米片是通过还原硝酸镍溶液而制得的,而硝酸镍溶液是通过应用黄aga胶水提取物而获得的,该提取物能够起还原和稳定剂的作用。在下文中,通过FESEM,EDS,XRD,UV-Vis和FT-IR技术鉴定了黄of胶稳定的NiO纳米片的物理和化学性质。根据XRD图谱,这些特定的纳米片具有立方结构和群空间Fm3m,以及与FESEM测量结果一致的约18至43nm的平均尺寸。此外,我们已经评估了黄aga胶稳定的NiO纳米片对亚甲基蓝(MB)和甲基橙(MO)染料降解的光催化活性。进行的光催化评估表明,纳米片可以在210分钟内降解82%的MO,在300分钟内降解60%的MB。通过MTT分析研究了黄aga胶稳定的NiO纳米片对人胶质母细胞瘤癌细胞(U87MG)的细胞毒性,同时在获得的结果中发现抑制浓度(IC50)为125 µg / mL。
更新日期:2020-03-06
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